CHeartED (Congenital Heart and Environment/Epidemiological Database)
The mission of CHeartED is to identify genetic and environmental pathways that can be modified with the goal of reducing preventable CVM incidence.
Central to the project is the development of a bioinformatics tool complemented by an open-access Wiki-based database. The bioinformatics tool will combine the sequence data and expression data generated by the human and mouse studies with morphology and literature to prioritize genes and generate hypotheses. The Wiki, which will contain existing and new genetic and environmental knowledge on heart development, will be an aid for many groups working on cardiovascular development and a novel means of disseminating our findings.
This work is supported by the European Community's 7th Framework Programme contract ('CHeartED') HEALTH-F2-2008-223040.